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Frailty is the most challenging expression of population ageing and it is thought that 10% of people aged over 65 years and 25-50% of those aged over 85 years have frailty. Frail older people have increased risk of morbidity, institutionalization and death, resulting in being a burden to these individuals, their families, health care services and society. Frailty can be defined as a geriatric syndrome characterized by weakness, weight loss and low activity that is associated with adverse health outcomes. Frailty manifests as an age-related, biological vulnerability to stressors and decreased physiological reserves yielding a limited capacity to maintain homeostasis.
At birth human body has ~ 80 million active stem cells and at age 40 we have less than 25 million active stem cells which is insufficient to maintain the organs from the degeneration process. At this stage the human body requires additional immune power and sufficient number of active stem cells to restore the wear and tear of tissues and organs.
Investigation of the product
NK cell – boost the immune system
Mesenchymal Stem cell – repair and regenerate the damaged or dysfunctional cells
Immune cell enhancement
Aging changes the physiological function of the immune system. This can result in an increased risk of sickness including cancer. Thus, to boost up the immune system through introduction of live immune cells [Natural Killer Cells (NK)] is a unique therapeutic strategy for frailty.
Stem cell for regeneration
Among other factors, aging is mostly dependent on the total active stem cells population. Thus, the introduction of young and healthy stem cells potentially slows down or reverses the frailty symptoms.
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