top of page
  • drjmohan

Mesenchymal Stem/Stromal Cell Therapy for Renal Artery Stenosis

Renal artery stenosis (RAS) results in "hypertension and post-stenotic kidney damage, which may become irresponsive to restoration of arterial patency. Rather than mere losses of blood flow or oxygen supply, irreversible intrarenal microvascular rarefaction, tubular injury, and

interstitial fibrosis are now attributed to intrinsic pathways activated within the kidney, focusing attention on the kidney parenchyma as a therapeutic target. Several regenerative approaches involving the delivery of reparative cells or products have achieved kidney repair in experimental models of RAS and the delivery of mesenchymal stem/stromal cells (MSCs) has already been translated to human subjects with RAS with promising results."

Image from Wikipedia.

"Leman L.O. (2021) Cell-based regenerative medicine for renovascular disease. Trends in Molecular Medicine. DOI:


Recent Posts

See All

Producing Heart Muscle Cells to Repair Damaged Hearts

Chronic heart failure is the most common reason for hospital admissions and one of the most frequent causes of death in the western world. Scientists around the world are therefore working on strategi

Stem Cell Therapy for Autoimmune Diseases

"Autoimmune diseases, chronic in nature, are generally hard to alleviate. Present long-term treatments with available drugs such as steroids, immune-suppressive drugs, or antibodies have several debil


bottom of page