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Should we be saving/storing our children's decidous (milk) teeth or our wisdom teeth

"Adult stem cells can be isolated from several adult tissues, such as umbilical cord, bone marrow, adipose tissue, skin, and dental tissue. The non-invasive methods of extracting dental stem cells (DSCs) from both permanent and deciduous teeth compared to other cell types have made them interesting and viable sources of stem cells for regenerative therapy. The mouth and surrounding dental tissues are enriched with several stem cells types, including dental pulp stem cells (DPSCs), periodontal ligament stem cells (PDLSCs), stem cells of apical papilla (SCAP), and dental follicle stem cells (DFSCs) of wisdom teeth, salivary grand stem cells (SGSCs), gingival mesenchyme stem cells (GMSCs), and stem cells from human exfoliated deciduous dental pulp (SHED). Interestingly, these cells have the potential to not only regenerate to cells of dental origin. but also to regenerate to other cell types, such as cardiac cells, neural cells, muscles cells, hepatocytes cells, pancreatic cells, bone cells, and others, under the proper signaling and environmental conditions."

"This systematic review demonstrated the growing body of evidence supporting the role of DSCs in the field of modern generative medicine. The noninvasive methods of isolating these cells compared to non-dental stem cells make them promising potential sources for the treatment of chronic and devastating diseases. However, more studies are needed to develop the proper guidelines as to cases in which DSCs can be considered an accurate and reliable tool for modern regenerative medicine in clinical trials."

Alhazzazi T.Y., Alghamdi F.T. (2021) Clinical Applications of Dental Stem Cells in Modern Regenerative Medicine: A Systematic Review with Updates. Nigerian Journal of Clinical Practice. DOI: 10.4103/njcp.njcp_498_20

More Information on the Regenerative Potential of Dental Stem Cells can be retrieved from this publication (2016).


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