"Based on extensive previous research, the underlying mechanisms of action that lead to the development of neurological diseases remain under investigation. The promise of SC transplantation increases daily, with excellent results reported in animal models. However, human trials must still be performed, although some small-scale experiments have been conducted, which have revealed the potential for severe side effects. The treatment of individual neurological disorders will be associated with different pathophysiological conditions; therefore, transplantation therapy must be performed under optimal conditions with minimal risk. Before performing transplantations in humans, basic research remains essential."
Rahman MM, Islam MR, Islam MT, Harun-Or-Rashid M, Islam M, Abdullah S, Uddin MB, Das S, Rahaman MS, Ahmed M, Alhumaydhi FA, Emran TB, Mohamed AA, Faruque MRI, Khandaker MU, Mostafa-Hedeab G. Stem Cell Transplantation Therapy and Neurological Disorders: Current Status and Future Perspectives. Biology (Basel). 2022 Jan 17;11(1):147. doi: 10.3390/biology11010147. PMID: 35053145; PMCID: PMC8772847.