"The vast advantages of using exosomes over MSCs have shifted the focus on these nano-platforms. The MSCs derived exosomes can be a novel intervention for treating the current COVID-19 pandemic situation due to their regenerative, im-munomodulatory, and anti-microbial properties. With upcoming reports and clinical studies using these proposed novel therapeutic interventions, exosomes can be established as cell-free therapeutics and drug delivery modality worldwide. This is the need of the hour and must be looked into as a potential nano-intervention for treating critically ill patients.
Displaying such a diverse range of advantageous properties including their spectral curability, and their capability to be used as a drug carrier, make exosomes an ideal candidate for clinical applications, and as an off the shelf therapeutics."
Pinky, Gupta S., Krishnakumar V., Sharma Y., Dinda A.K., Mohanty S. (2021) Mesenchymal Stem Cell Derived Exosomes: a Nano Platform for Therapeutics and Drug Delivery in Combating COVID-19. Stem Cell Reviews and Reports 17:33–43. https://doi.org/10.1007/s12015-020-10002-z.