Regenerative capacity of Adipose Derived Stem Cells vs Mesenchymal Stem Cells
Updated: May 28, 2020
Adipose tissue is now the popular choice of origin of stem cells "due its accessibility, abundance and less painful collection procedure when compared with other sources. The adipose derived stem cells (ADSCs) that it contains can be maintained and expanded in culture for long periods of time without losing their differentiation capacity, leading to large cell quantities being increasingly used in cell therapy purposes.
Many reports showed that ADSCs-based cell therapy products demonstrated optimal efficacy and efficiency in some clinical indications for both autologous and allogeneic purposes, hence becoming considered as potential tools for replacing, repairing, and regenerating dead or damaged cells. In this review, we analyzed the therapeutic advancement of ADSCs in comparison to bone marrow (BM) and umbilical cord (UC)-mesenchymal stem cells (MSCs). .
Clinical outcomes improvement suggested that these cells hold great promise in stem cell-based therapies in neurodegenerative, cardiovascular, and auto-immune diseases."
Also incorporates a table which summarises results of previous clinical studies using ADSCs as compared to those with BM-and UC-MSCs.
Int. J. Mol. Sci. 2019, 20, 2523; doi:10.3390/ijms20102523